Editorial: Microenvironment-Derived Stem Cell Plasticity

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Editorial: Microenvironment-Derived Stem Cell Plasticity

1 Institute of Cell Biology, Histology and Embryology, Medical University Graz, Graz, Austria, 2 Institute for Medical Research, University of Belgrade, Belgrade, Serbia, 3 AO Research Institute, Davos, Switzerland, 4 IZKF Group Tissue Regeneration in Musculoskeletal Diseases, Orthopedic Center for Musculoskeletal Research, University of Würzburg, Würzburg, Germany, 5 Belgrade Metropolitan Univ...

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STEM CELL Stem cell plasticity

The quintessential stem cell is the embryonal stem (ES) cell which has unlimited self-renewal and multipotent differentiation potential. Stem cells have also been identified in most tissues. Compared with ES cells, tissue specific stem cells have less self-renewal ability and, although they differentiate into multiple lineages, they are not multipotent. A large number of recent published studie...

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Engineering the stem cell microenvironment.

Multipotent stem cells in the body facilitate tissue regeneration, growth, and wound healing throughout life. The microenvironment in which they reside provides signals that direct these progenitors to proliferate, differentiate, or remain dormant; these factors include soluble molecules, the extracellular matrix, neighboring cells, and physical stimuli. Recent advances in the culture of embryo...

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The neural stem cell microenvironment∗

1. The embryonic neural stem cell (NSC) microenvironment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 1.1. The VZ microenvironment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 1.2. Signalling in the embryonic NSC microenvironment . . . . . . . . . . . . . . . . . . . . . . . . . . . ....

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ژورنال

عنوان ژورنال: Frontiers in Cell and Developmental Biology

سال: 2017

ISSN: 2296-634X

DOI: 10.3389/fcell.2017.00082